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Bills vs. Chargers Prediction, Odds, Pick For NFL Week 3

  • The Chargers have stumbled to a shocking 0-2 start — losing 26-14 in both Weeks 1 and 2 — and are the first team ever to begin 0-2 after losses to two teams that each had at least 14 losses the prior season.
  • The Bills are rolling under new coach Joe Brady, leading the league in scoring (38.5 ppg) and pace, with Josh Allen an early MVP favorite (nine TDs, zero turnovers).
  • Game to watch: Buffalo is favored (Bills -7.5 on FanDuel as of Sept. 27), but their struggling defense gives the Chargers a real chance to bounce back — perfect small-talk debate: offense vs. defense.
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