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Illinois vs. Duke Prediction, Odds, Pick For College Football Week 2

  • Rematch Saturday after Illinois blew out Duke 45-19 last season — but both teams have new quarterbacks this year.
  • Illinois looked sharp in a 42-23 opener (Katin Houser had three TD passes and a rushing score) and is tough at home — Bielema has won six straight season openers.
  • Duke leaned on RB Nate Sheppard’s 227-yard performance in Week 1 while new QB Walker Eget had a modest debut (50%, 131 yards, no TDs).
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