- Jaguars routed the Browns 34-10, a dominant Week 1 that left Cleveland coach Todd Monken defending his staff after Deshaun Watson was sacked five times.
- Bills edged the Texans 36-31 — Joe Brady famously celebrated his first win shirtless while Josh Allen and new-look receivers (DJ Moore, Dalton Kincaid) delivered big plays.
- Vikings starter Kyler Murray exited with a concussion in his first start, with veteran Carson Wentz stepping in and the team's QB competition suddenly in flux.
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