- No. 6 Indiana (6-1) brings a high-powered offense (36.6 ppg) and stingy defense (12.9 ppg) to Ann Arbor — are they the real Big Ten threat this year?
- Michigan (4-2) leans on a tough defense at home and needs QB Bryce Underwood to handle heavy pressure for the Wolverines to stay competitive.
- Hoosiers are 6-point favorites (moneyline -258); does Michigan have enough at home to pull the upset or cover the spread?