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Indiana vs. Nebraska Prediction, Odds, Picks for College Football Week 6

  • Nebraska is 5-0 under Matt Rhule, scoring 30+ in every game and riding momentum — a win would be a signature upset chance against the defending champs.
  • Indiana has won 21 straight, boasts one of the nation’s top defenses and protects the ball (only one turnover all season).
  • Both teams pair high-powered offenses with stingy defenses, so expect a fast, high-scoring Big Noon Kickoff showdown.
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