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Cardinals vs. Lions Prediction, Odds, Pick For NFL Week 5

  • Week 5 matchup: Lions (2-2) visit Cardinals, who have lost three straight — both teams are struggling to stop opponents, so it’s a tense spot for Arizona with tougher games ahead.
  • Offense-heavy: Detroit averages about 30 points per game with Jared Goff (9 TDs, 0 INTs) leading the charge; Arizona still has playmakers like TE Trey McBride and rookie Jeremiyah Love (153 rushing yards last two weeks).
  • Expect a shootout: both defenses rank among the worst in yards/points allowed, and analysts are leaning toward the over — should make for lively, high-scoring small talk.
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