- No. 9 Ole Miss travels to Nashville to face No. 24 Louisville — spotlight on Ole Miss playmakers Trinidad Chambliss and Kewan Lacy versus Louisville’s dynamic RB Isaac Brown as Jeff Brohm chases an upset.
- No. 4 Notre Dame meets Wisconsin at Lambeau Field — a neutral-site, marquee matchup that could define early-season momentum.
- Weekend packed with ranked teams and upset potential, offering plenty of conversation fodder for fantasy, betting or just casual game-day debate.
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