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2026 MLB ALDS Odds: Guardians Favored Over White Sox

  • Guardians are slight favorites (about -145 moneyline on Oct. 1), but several outcome bets still give the White Sox upset potential.
  • The teams are familiar—Cleveland won the season series narrowly, 7–6—so the matchup should be tightly contested.
  • White Sox have momentum after sweeping the Astros for their first playoff win since 2005; Guardians have been regular postseason participants (3 of the last 4 years) and made the 2024 ALCS.
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