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2026 NFL Odds: Which Teams Are Favored To Vie For Super Bowl LXI?

  • DraftKings lists Bills vs. 49ers as the favorite Super Bowl LXI matchup at +960 (about a 9.4% implied chance).
  • The 49ers show up everywhere — five of the shortest matchups and +540 to win the Super Bowl — despite not winning a title since 1995.
  • Buffalo appears in more top matchups than any other team (seven), while the Jaguars are the most frequent other AFC threat; Jaguars-Bears (+2500) is the cheapest pairing that doesn’t include San Francisco or Buffalo.
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